Cyclo(RGDyK) b

CAS No. 217099-14-4

Cyclo(RGDyK) b ( )

Catalog No. M30392 CAS No. 217099-14-4

Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Cyclo(RGDyK) b
  • Note
    Research use only, not for human use.
  • Brief Description
    Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.
  • Description
    Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.(In Vitro):Cyclo(RGDyK) (c(RGDyK(SAA)) shows high affinity and selectivity for αVβ3 over αVβ5 (IC50=4000 nM) and αIIbβ3 (IC50=3000 nM).
  • Synonyms
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Integrin
  • Recptor
    IC50: 20 nM (αVβ3 Integrin), 3000 nM (αIIbβ3 Integrin), 4000 nM (αVβ5 Integrin)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    217099-14-4
  • Formula Weight
    619.7
  • Molecular Formula
    C27H41N9O8
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Haubner R, et al. Glycosylated RGD-containing peptides: tracer for tumor targeting and angiogenesis imaging with improved biokinetics. J Nucl Med. 2001 Feb;42(2):326-36.
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